In the wind industry, estimating extreme wind speeds over a 50-year period using one year of data presents challenges due to the limited representation of extreme events. This study proposes a methodology that combines measurements from Cabauw (The Netherlands) with the ASPIRE 100x100 m horizontal resolution large-eddy simulation. Using 20 years of Cabauw measurements as a reference, we compared four methods to estimate the 50-year wind speed (<em>V<sub>ref</sub></em><sub> </sub>). The results show that combining ASPIRE with one year of measurements improves <em>V<sub>ref</sub></em> estimates, matching the 20-year reference within 3 %. With these promising results, our aim is to apply this methodology to 12-month wind measurement campaigns from the wind industry.